Cardiac complications in Behçet's disease.
作者： Ü. Türsen , B. Ulubaş , T. İrfan Kaya , H. Pekdemir , G. İkizoğlu
DOI: 10.1046/J.1365-2230.2002.01090.X
关键词: Complication 、 Systemic disease 、 Vasculitis 、 Disease 、 Internal medicine 、 Uveitis 、 Gene mutation 、 Medicine 、 Pathology 、 Vascular disease 、 Behcet's disease 、 Gastroenterology
摘要: Summary Behcet's disease (BD) is a multisystem of unknown aetiology characterized by chronic relapsing oro-genital ulcers, uveitis, and systemic involvement including articular, gastrointestinal, cardiopulmonary, neurologic vascular pathology. Vascular observed in 30% cases. Although the pathogenic mechanisms underlying thrombotic disposition BD are not well known, prothrombin (PT) gene mutations may be one factor that contributes to development this disorder. We report case with PT mutation, presenting cardiovascular involvement.
blackwell-synergy.com参考文章(12)
M. ÖZKAN, O. EMEL, M. ÖZDEMIR, S. YURDAKUL, H. KOCAK, H. ÖZDOGAN, V. HAMURYUDAN, A. DIRICAN, H. YAZICI, M-mode, 2-D and Doppler echocardiographic study in 65 patients with Behçet's syndrome European Heart Journal. ,vol. 13, pp. 638- 641 ,(1992) , 10.1093/OXFORDJOURNALS.EURHEARTJ.A060228
Andreas Hillarp, Bengt Zӧller, Peter J Svensson, Bjӧrn Dahlbäck, The 20210 A allele of the prothrombin gene is a common risk factor among Swedish outpatients with verified deep venous thrombosis. Thrombosis and Haemostasis. ,vol. 78, pp. 990- 992 ,(1997) , 10.1055/S-0038-1657674
Niels H. Gehring, Ute Frede, Gabriele Neu-Yilik, Patrick Hundsdoerfer, Barbara Vetter, Matthias W. Hentze, Andreas E. Kulozik, Increased efficiency of mRNA 3' end formation: a new genetic mechanism contributing to hereditary thrombophilia. Nature Genetics. ,vol. 28, pp. 389- 392 ,(2001) , 10.1038/NG578
SR Poort, FR Rosendaal, PH Reitsma, RM Bertina, A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood. ,vol. 88, pp. 3698- 3703 ,(1996) , 10.1182/BLOOD.V88.10.3698.BLOODJOURNAL88103698
K. M. El-Ramahi, M. E. Fawzy, J. O. Sieck, G. Vanhaleweyk, Cardiac and Pulmonary Involvement in Behcet's Disease Scandinavian Journal of Rheumatology. ,vol. 20, pp. 373- 376 ,(1991) , 10.3109/03009749109096815
Hasan Yazici, THE PLACE OF BEHCET'S SYNDROME AMONG THE AUTOIMMUNE DISEASES International Reviews of Immunology. ,vol. 14, pp. 1- 10 ,(1997) , 10.3109/08830189709116840
Umit Tursen, Tamer Irfan Kaya, Gulcin Eskandari, Ozgur Gunduz, Müjde Yazar, Guliz Ikizoglu, Ugur Atik, None, Association of factor V Leiden and prothrombin gene mutation with Behçet's disease. Archives of Dermatological Research. ,vol. 293, pp. 537- 539 ,(2001) , 10.1007/PL00007469
Lisa A. Mendes, Lawrence L. Magraw, Gabriel S. Aldea, Ravin Davidoff, Right Ventricular Thrombus: An Unusual Manifestation of Behçet's Disease Journal of the American Society of Echocardiography. ,vol. 7, pp. 438- 440 ,(1994) , 10.1016/S0894-7317(14)80208-3
H Yazici, Y Tuzun, H Pazarli, S Yurdakul, Y Ozyazgan, H Ozdogan, S Serdaroglu, M Ersanli, B Y Ulku, A U Muftuoglu, Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Behçet's syndrome. Annals of the Rheumatic Diseases. ,vol. 43, pp. 783- 789 ,(1984) , 10.1136/ARD.43.6.783
Nesrin Mogulkoc, Malcolm I. Burgess, Paul William Bishop, Intracardiac Thrombus in Behçet's Disease: A Systematic Review Chest. ,vol. 118, pp. 479- 487 ,(2000) , 10.1378/CHEST.118.2.479