Rapid Gastric Emptying/Pyloric Dysfunction

作者: Alexander Pontikos , Thomas L. Abell

DOI: 10.1007/978-3-319-59352-4_26

关键词: GastroenterologyGastric emptyingNauseaAcarboseStomachInternal medicineDiarrheaPalpitationsIngestionDumping syndromeMedicine

摘要: Rapid gastric emptying, also known as dumping syndrome, is a condition that results from the transition of undigested food stomach to small intestine. Symptoms include diarrhea, nausea, and epigastric pain, well tachycardia, palpitations, hypotension. emptying has been linked surgeries, but recently diabetes mellitus type II viral illnesses have caused this condition. The diagnosis syndrome based on clinical symptoms confirmed scintigraphy revealing rapid emptying. An oral glucose challenge can be performed which provokes similar symptoms. pathophysiology most likely multifactorial, involving hormones (VIP, serotonin, GLP-1), fluid shifts, characteristics chyme, or bolus. Treatment aimed around dietary modifications first-line recommendation. Small, more frequent complex carbohydrate meals with ingestion liquids 1 h after solid are suggested. Acarbose, anticholinergic medications, somatostatin, electrical stimulation shown help not controlled changes. Research in areas etiology, physiology, treatment continued interest world, hope provide answers an evolving dysfunction.

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