Wernicke's encephalopathy associated with hemodialysis: report of two cases and review of the literature.

摘要: Two rare cases of Wernicke's encephalopathy (WE) in non-alcoholic patients on hemodialysis (HD) are reported. They presented with the clinical triad WE (ophthalmoplegia, ataxia and disturbance consciousness) intravenous administration thiamine led to complete elimination these manifestations. Reduced plasma levels prior confirmed diagnosis WE. Interestingly, a reduction by about half was seen one HD, suggesting that thiamine, water-soluble vitamin, can be depleted HD. In literature, nine HD-dependent have been reported develop WE, seven whom were diagnosed postmortem. Their premortem diagnoses included uremic encephalopathy, dysequilibrium syndrome dialysis dementia, which often complicate HD present symptoms similar those We therefore emphasize even though complication, should suspected all who at least