The Morbidity and Mortality Associated With Overweight and Obesity in Adulthood

摘要: SUMMARY Background: Overweight and obesity are generally thought to elevate morbidity mortality. New data call this supposed association into question. Methods: The Cochrane, Pubmed, other databases were systematically searched for a combination of relevant terms subject headings. Meta-analyses cohort studies based on the German population evaluated possible associations between overweight/ adult Case-control cross-sectional excluded. Results: A total 27 meta-analyses 15 eval uated. overall mortality overweight persons (body mass index [BMI] 25–29.9 kg/m 2 ) is no higher than that normal weight (BMI 18.5–24.9 ), but their from individual diseases elevated, diminished or unchanged, depending particular disease. unknown. Both >30 associated with increased disease-specific some diseases, decreased unchanged others. In general, confers risk overweight. Morbidity markedly influenced by patient’s age, sex, ethnic origin, social status. external validity comparative predictive performance (c-statistic) BMI, waist circumference, ratio hip circumference cannot be determined available analyses. Conclusion: prevailing notion increases mortality, as compared socalled weight, in need further specification. Obesity, however, indeed an elevated most studied.