作者: Rajiv Sankaranarayanan , Graeme Kirkwood , Katharine Dibb , Clifford J. Garratt
DOI: 10.1155/2013/976976
关键词: Pulmonary vein 、 Atrial fibrillation 、 Risk factor 、 Medicine 、 Pediatrics 、 Pathogenesis 、 Treatment options 、 Incidence (epidemiology) 、 Epidemiology 、 Disease 、 Internal medicine 、 Cardiology
摘要: The incidence and prevalence of atrial fibrillation (AF) are projected to increase significantly worldwide, imposing a significant burden on healthcare resources. disease itself is extremely heterogeneous in its epidemiology, pathophysiology, treatment options based individual patient characteristics. Whilst ageing well recognised be an independent risk factor for the development AF, this condition also affects young whom frequently symptomatic troublesome. Traditional thinking suggests that causal factors pathogenesis with structurally normal atria but electrophysiological "triggers" form pulmonary vein ectopics leading lone AF stark contrast elderly who have primarily due abnormal substrate consisting fibrosed dilated acting concert triggers. However, there can exceptions rule as increasing evidence structural abnormalities patients "lone AF," present idiopathic AF. These reports seem blurring distinction pathophysiology so-called versus elderly. Moreover availability improved modern investigational diagnostic techniques, novel causes being reported thereby seemingly consigning diagnosis AF" rather mythical existence. We shall elucidate paper differences seen causes, pathogenesis, clinical features elderly, requiring clearly defined management strategies tackle arrhythmia associated consequences.