The Risk of Cardiovascular Events After an Acute Coronary Event Remains High, Especially During the First Year, Despite Revascularization.

作者: Emad Abu-Assi , Andrea López-López , Violeta González-Salvado , Alfredo Redondo-Diéguez , Carlos Peña-Gil

DOI: 10.1016/J.REC.2015.06.015

关键词: CardiologyStrokeAcute coronary syndromeInternal medicineInfarctionMedicineRevascularizationIncidence (epidemiology)Risk assessmentMyocardial infarctionRetrospective cohort study

摘要: Abstract Introduction and objectives There is little information on the incidence predictors of infarction, stroke, or cardiovascular death after acute coronary syndrome. We investigated these aspects developed tools for predicting events according to time their occurrence. Methods A retrospective study was conducted 4858 patients who survived an event. analyzed myocardial during first year (n = 4858) vs successive years (n = 4345 free composite year). Results were 329 in (cumulative function: 7.3% person-years) 616 (21.5% person-years; follow-up 4.9 ± 2.4 years). The risk per tertile 2.5% person-years low-risk ( 6 points) P C  statistic, 0.74 0.69, respectively;  (Hosmer-Lemeshow test) ≥ 0.44 Conclusion recurrence remains high level can be easily quantified with acceptable predictive ability.

参考文章(29)
Sergio Raposeiras-Roubín, Emad Abu-Assi, Pilar Cabanas-Grandío, Rosa María Agra-Bermejo, Santiago Gestal-Romarí, Eva Pereira-López, Rubén Fandiño-Vaquero, Belén Álvarez-Álvarez, Cristina Cambeiro, Marta Rodríguez-Cordero, Pamela Lear, Amparo Martínez-Monzonís, Carlos Peña-Gil, José María García-Acuña, José Ramón González-Juanatey, Walking Beyond the GRACE (Global Registry of Acute Coronary Events) Model in the Death Risk Stratification During Hospitalization in Patients With Acute Coronary Syndrome JACC: Cardiovascular Interventions. ,vol. 5, pp. 1117- 1125 ,(2012) , 10.1016/J.JCIN.2012.06.023
S Chung, Pegasus-Timi, A Timmis, L Pasea, S Denaxas, D Stogiannis, AD Shah, C Emmas, H Hemingway, M Pujades-Rodriguez, E Rapsomaniki, Health outcomes in patients with stable coronary artery disease following myocardial infarction; construction of a PEGASUS-TIMI-54 like population in UK linked electronic health records In: (pp. p. 363). (2014). ,(2014)
Lech Polonski, Mariusz Gasior, Marek Gierlotka, Tadeusz Osadnik, Zbigniew Kalarus, Maria Trusz-Gluza, Marian Zembala, Krzysztof Wilczek, Andrzej Lekston, Tomasz Zdrojewski, Michal Tendera, A comparison of ST elevation versus non-ST elevation myocardial infarction outcomes in a large registry database: Are non-ST myocardial infarctions associated with worse long-term prognoses? International Journal of Cardiology. ,vol. 152, pp. 70- 77 ,(2011) , 10.1016/J.IJCARD.2010.07.008
Lilian Grigorian-Shamagian, Fernando Otero Raviña, Emad Abu Assi, Rafael Vidal Perez, Elvis Teijeira-Fernandez, Alfonso Varela Roman, Laura Moreira Sayagues, Jose Ramon Gonzalez-Juanatey, Why and when do patients with heart failure and normal left ventricular ejection fraction die? Analysis of >600 deaths in a community long-term study American Heart Journal. ,vol. 156, pp. 1184- 1190 ,(2008) , 10.1016/J.AHJ.2008.07.011
Matthew J. Taylor, Paul A. Scuffham, Patrick L. McCollam, David E. Newby, Acute coronary syndromes in Europe: 1-year costs and outcomes. Current Medical Research and Opinion. ,vol. 23, pp. 495- 503 ,(2007) , 10.1185/030079906X167462
Jennifer G Robinson, Michel Farnier, Michel Krempf, Jean Bergeron, Gérald Luc, Maurizio Averna, Erik S Stroes, Gisle Langslet, Frederick J Raal, Mahfouz El Shahawy, Michael J Koren, Norman E Lepor, Christelle Lorenzato, Robert Pordy, Umesh Chaudhari, John JP Kastelein, None, Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events The New England Journal of Medicine. ,vol. 372, pp. 1489- 1499 ,(2015) , 10.1056/NEJMOA1501031
Deepak L Bhatt, Kim A Eagle, E Magnus Ohman, Alan T Hirsch, Shinya Goto, Elizabeth M Mahoney, Peter WF Wilson, Mark J Alberts, Ralph D’Agostino, Chiau-Suong Liau, Jean-Louis Mas, Joachim Röther, Sidney C Smith, Geneviève Salette, Charles F Contant, Joseph M Massaro, Ph Gabriel Steg, for the REACH Registry Investigators, None, Comparative Determinants of 4-Year Cardiovascular Event Rates in Stable Outpatients at Risk of or With Atherothrombosis JAMA. ,vol. 304, pp. 1350- 1357 ,(2010) , 10.1001/JAMA.2010.1322
Matthew T. Roe, John C. Messenger, William S. Weintraub, Christopher P. Cannon, Gregg C. Fonarow, David Dai, Anita Y. Chen, Lloyd W. Klein, Frederick A. Masoudi, Charles McKay, Kathleen Hewitt, Ralph G. Brindis, Eric D. Peterson, John S. Rumsfeld, Treatments, trends, and outcomes of acute myocardial infarction and percutaneous coronary intervention. Journal of the American College of Cardiology. ,vol. 56, pp. 254- 263 ,(2010) , 10.1016/J.JACC.2010.05.008
Irene R. Dégano, Roberto Elosua, Jaume Marrugat, Epidemiología del síndrome coronario agudo en España: estimación del número de casos y la tendencia de 2005 a 2049 Revista Espanola De Cardiologia. ,vol. 66, pp. 472- 481 ,(2013) , 10.1016/J.RECESP.2013.01.019
William J Rogers, Paul D Frederick, Edna Stoehr, John G Canto, Joseph P Ornato, C Michael Gibson, Charles V Pollack Jr, Joel M Gore, Nisha Chandra-Strobos, Eric D Peterson, William J French, National Registry of Myocardial Infarction Investigators, Trends in presenting characteristics and hospital mortality among patients with ST elevation and non-ST elevation myocardial infarction in the National Registry of Myocardial Infarction from 1990 to 2006 American Heart Journal. ,vol. 156, pp. 1026- 1034 ,(2008) , 10.1016/J.AHJ.2008.07.030