Preventing pediatric cardiomyopathy: a 2015 outlook

摘要: Cardiomyopathies in children encompass a broad range of diseases, both genetic and acquired, which manifest as primary cardiac disorder or cardiomyopathy secondary to systemic disease. The burden this group disorders is substantial, growing on global scale. availability disease altering treatments limited, therefore focused review the prevention cardiomyopathies justified. In review, we address by dealing with root causes at molecular, clinical population level. Recent years have yielded promising returns basic research related gene-targeted therapy, specific anti-viral therapies modification effects cardiotoxic drugs. Much work remains be done fields vaccine development, public health adoption available treatments. Effective field will require that diagnostic methods are refined, made more broadly, from imaging gene testing. our knowledge today derived use registries, successfully catalogued detailed phenotype affected patients, provided long-term longitudinal follow up individuals.