Rapid evolution of animal mitochondrial DNA.

摘要: Abstract Mitochondrial DNA was purified from four species of higher primates (Guinea baboon, rhesus macaque, guenon, and human) digested with 11 restriction endonucleases. A cleavage map constructed for the mitochondrial each species. Comparison maps, aligned respect to origin direction replication, revealed that differ one another at most sites. The degree divergence in nucleotide sequence these sites calculated fraction shared by pair By plotting against time divergence, rate base substitution could be initial slope curve. value obtained, 0.02 substitutions per million years, compared single-copy nuclear DNA. evolution genome appears exceed a factor about 10. This high may due, part, an elevated mutation Because evolution, is likely extremely useful molecule employ high-resolution analysis evolutionary process.