Epigenetic mechanisms as targets and companions of viral assaults

作者: Ingemar Ernberg , Mohsen Karimi , Tomas J. Ekström

DOI: 10.1111/J.1749-6632.2011.06357.X

关键词: Cellular differentiationBiologyEpigeneticsNeurosciencePhenotypeBioinformaticsStem cellGeneral Biochemistry, Genetics and Molecular BiologyHistory and philosophy of science

摘要: The past decade has seen an explosion of interest for understanding epigenetic mechanisms. This is not surprising since it been obvious that we need this knowledge to understand basic biology, such as cellular differentiation, stem cell maintenance, and pathological phenotype, etiology, therapy responses. It also evident the constant exposure environment affects our functional genomes through short review will bring up general principles mechanisms well how viral infections, which constantly affect physiology, can interphase with these in order evade host defense promote their own multiplication and/or latency.

参考文章(88)
A. M. Deaton, A. Bird, CpG Islands and the Regulation of Transcription Genes & Development. ,vol. 25, pp. 1010- 1022 ,(2011) , 10.1101/GAD.2037511
Jane C Murphy, Wolfgang Fischle, Eric Verdin, John H Sinclair, Control of cytomegalovirus lytic gene expression by histone acetylation The EMBO Journal. ,vol. 21, pp. 1112- 1120 ,(2002) , 10.1093/EMBOJ/21.5.1112
Dana C. Dolinoy, Jennifer R. Weidman, Robert A. Waterland, Randy L. Jirtle, Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome Environmental Health Perspectives. ,vol. 114, pp. 567- 572 ,(2006) , 10.1289/EHP.8700
F. Rosl, A. Arab, B. Klevenz, H. zur Hausen, The effect of DNA methylation on gene regulation of human papillomaviruses. Journal of General Virology. ,vol. 74, pp. 791- 801 ,(1993) , 10.1099/0022-1317-74-5-791
R. W. Honess, U. A. Gompels, B. G. Barrell, M. Craxton, K. R. Cameron, R. Staden, Y.-N. Chang, G. S. Hayward, Deviations from expected frequencies of CpG dinucleotides in herpesvirus DNAs may be diagnostic of differences in the states of their latent genomes. Journal of General Virology. ,vol. 70, pp. 837- 855 ,(1989) , 10.1099/0022-1317-70-4-837
Lualhati Harkins, Andrea L Volk, Minu Samanta, Ivan Mikolaenko, William J Britt, Kirby I Bland, Charles S Cobbs, Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer The Lancet. ,vol. 360, pp. 1557- 1563 ,(2002) , 10.1016/S0140-6736(02)11524-8
Prasanna M. Bhende, William T. Seaman, Henri-Jacques Delecluse, Shannon C. Kenney, BZLF1 Activation of the Methylated Form of the BRLF1 Immediate-Early Promoter Is Regulated by BZLF1 Residue 186 Journal of Virology. ,vol. 79, pp. 7338- 7348 ,(2005) , 10.1128/JVI.79.12.7338-7348.2005
J. Minarovits, S. Minarovits-Kormuta, B. Ehlin-Henriksson, K. Falk, G. Klein, I. Ernberg, Host cell phenotype-dependent methylation patterns of Epstein-Barr virus DNA. Journal of General Virology. ,vol. 72, pp. 1591- 1599 ,(1991) , 10.1099/0022-1317-72-7-1591
N. Hollink, M. Dzabic, N. Wolmer, L. Boström, A. Rahbar, High prevalence of an active human cytomegalovirus infection in patients with colonic diverticulitis. Journal of Clinical Virology. ,vol. 40, pp. 116- 119 ,(2007) , 10.1016/J.JCV.2007.07.008