Orthotopic Liver Transplantation in Children: Two-Year Experience with 47 Patients
作者： BJ Zitelli , JJ Malatack , BW Shaw , TE Starzl , Jr Jc Gartner
DOI:
关键词: Chronic liver disease 、 Hypoplasia 、 Immunosuppression 、 Liver disease 、 Medicine 、 Liver transplantation 、 Surgery 、 Biliary atresia 、 Prednisone 、 Transplantation
摘要: During a 24-month period (May 1981 to May 1983), 47 pediatric patients (ranging in age from 7 months 18 years) underwent orthotopic liver transplantation using cyclosporine and prednisone. Major indications were biliary atresia/hypoplasia, metabolic disease. Thirty-two of 138 evaluated for the procedure died prior transplantation. Thirty are alive 6 29 later including 7/15 who required retransplantation. Twenty-one 32 at 1 year following initial All 30 survivors clinically well living home; only one has an abnormal bilirubin level. Serious, life-threatening medical surgical complications common during early With exception, deaths major rejection episodes occurred (before 120 days). relieved stigmata chronic disease, many have demonstrated catch-up growth. Liver is effective treatment end-stage
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