作者: Giorgia Podico , Igor F. Canisso , Robyn E. Ellerbrock , Nicholas W. Dias , Vitor R.G. Mercadante
DOI: 10.1016/J.THERIOGENOLOGY.2019.09.025
关键词: Gynecology 、 Gestation 、 Transrectal ultrasonography 、 Early Pregnancy Loss 、 Abortion 、 Heartbeat 、 Fetus 、 Repeated measures design 、 Medicine 、 Pregnancy
摘要: Abstract The present study aimed to compare two methods of prostaglandin-induced abortion in mares by determining blood markers (progesterone, estradiol-17β, alpha-fetoprotein, 13,14-dihydro-15-keto-prostaglandin-F2α (PGFM)), B-mode ultrasonographic parameters, and time until loss fetal heartbeat. It was hypothesized that intrauterine infusion cloprostenol results earlier compromise than intramuscular administration. Ovarian structures (number sizes follicles corpora lutea area), heartbeat, mobility thirteen singleton pregnancies were assessed daily transrectal ultrasonography induction pregnancy termination (60 ± 2 days gestation). Mares received 500 μg intramuscularly every 12 h (IM, n = 7) or once transcervically (TC, n = 6). After initial administration, examinations repeated at 6-h intervals heartbeat detected. Plasma progesterone, alpha-fetoprotein for five before after loss. In addition, plasma PGFM concentrations immediately administration (0 min), then 15, 30, 45 min, 1, 2, 3, 4, 6, Data analyzed using the MIXED procedure with measures SAS. Significance set P