Papillary cystic and solid tumors of the pancreas: A pancreatic embryonic tumor? Studies of three cases and cumulative review of the world's literature

摘要: Background. The papillary cystic and solid tumor of the pancreas is rare. It occurs predominantly in young women, most present a benign behavior. pathogenesis this has attracted number investigations but remains unclear. Methods. We three patients with review 289 others from world's literature, total 292 cases. On basis analyses clinical pathologic features reported cases, unusual been further explored. Results. Ninety percent were female, mean age 23.9 years. tumors usually quite large diameter 10.3 cm. Ninety-two these totally or partially cystic. Rupture capsule resulted hemoperitoneum eight five which without any identifiable cause. Forty-three (14.7%) have recognized as malignant. overall prognosis excellent an aggressive approach to resection indicated. Conclusions. results immunohistochemical staining electromicroscopy rather diverse, most, including current support hypothesis that originates pleuripotential embryonic stem cells. Thus term pancreatic seems preferable delineate origin reflect some its biologic characteristics.