Medical therapies in pituitary adenomas: Current rationale for the use and future perspectives

作者: Thomas Cuny , Anne Barlier , Richard Feelders , Georges Weryha , Leo J. Hofland

DOI: 10.1016/J.ANDO.2014.10.002

关键词: ProlactinomaPituitary neoplasmMedicineAcromegalySurgeryACTH-Secreting Pituitary AdenomaCushing's diseaseRadiation therapyAdenomaSomatostatin analogOncologyInternal medicine

摘要: Pituitary adenomas (PA) represent in the majority of cases, benign tumors whose treatment currently associate surgery, medical therapies and radiotherapy a multidisciplinary approach. While trans-sphenoidal surgery remains, except for prolactin-secreting adenomas, first-line PA, it can considerably be hampered by existence an invasive and/or aggressive tumor which are often requested. In this review, we extensively discuss, both at molecular clinical levels, used development different phenotypes pituitary adenomas.

参考文章(143)
C de Bruin, R A Feelders, A M Waaijers, P M van Koetsveld, D M Sprij-Mooij, S W J Lamberts, L J Hofland, Differential regulation of human dopamine D2 and somatostatin receptor subtype expression by glucocorticoids in vitro Journal of Molecular Endocrinology. ,vol. 42, pp. 47- 56 ,(2008) , 10.1677/JME-08-0110
Leonardo Vieira Neto, Evelyn de O. Machado, Raul M. Luque, Giselle F. Taboada, Jorge B. Marcondes, Leila M. C. Chimelli, Leonardo Pereira Quintella, Paulo Niemeyer, Denise P. de Carvalho, Rhonda D. Kineman, Mônica R. Gadelha, Expression analysis of dopamine receptor subtypes in normal human pituitaries, nonfunctioning pituitary adenomas and somatotropinomas, and the association between dopamine and somatostatin receptors with clinical response to octreotide-LAR in acromegaly. The Journal of Clinical Endocrinology and Metabolism. ,vol. 94, pp. 1931- 1937 ,(2009) , 10.1210/JC.2008-1826
WM Drake, CE Stiles, TA Howlett, AA Toogood, JS Bevan, RP Steeds, UK Dopamine Agonist Valvulopathy Group, None, A Cross-Sectional Study of the Prevalence of Cardiac Valvular Abnormalities in Hyperprolactinemic Patients Treated With Ergot-Derived Dopamine Agonists The Journal of Clinical Endocrinology & Metabolism. ,vol. 99, pp. 90- 96 ,(2014) , 10.1210/JC.2013-2254
Shlomo Melmed, Acromegaly pathogenesis and treatment Journal of Clinical Investigation. ,vol. 119, pp. 3189- 3202 ,(2009) , 10.1172/JCI39375
Tina Kienitz, Marcus Quinkler, Christian J Strasburger, Manfred Ventz, Long-term management in five cases of TSH-secreting pituitary adenomas: a single center study and review of the literature European Journal of Endocrinology. ,vol. 157, pp. 39- 46 ,(2007) , 10.1530/EJE-07-0098
Marcelo Páez-Pereda, Damian Kovalovsky, Ursula Hopfner, Marily Theodoropoulou, Uberto Pagotto, Eberhard Uhl, Marco Losa, Johanna Stalla, Yvonne Grübler, Cristina Missale, Eduardo Arzt, Günter K. Stalla, Retinoic acid prevents experimental Cushing syndrome Journal of Clinical Investigation. ,vol. 108, pp. 1123- 1131 ,(2001) , 10.1172/JCI11098
Richard A. Feelders, Leo J. Hofland, Medical Treatment of Cushing's Disease The Journal of Clinical Endocrinology and Metabolism. ,vol. 98, pp. 425- 438 ,(2013) , 10.1210/JC.2012-3126
Johan Verhelst, Roger Abs, Dominique Maiter, Annick van den Bruel, Mark Vandeweghe, Brigitte Velkeniers, Jean Mockel, Gerard Lamberigts, Patrick Petrossians, Peter Coremans, Charles Mahler, Achille Stevenaert, Jan Verlooy, Christian Raftopoulos, Albert Beckers, Cabergoline in the treatment of hyperprolactinemia: a study in 455 patients. The Journal of Clinical Endocrinology and Metabolism. ,vol. 84, pp. 2518- 2522 ,(1999) , 10.1210/JCEM.84.7.5810
Christiaan de Bruin, Alberto M. Pereira, Richard A. Feelders, Johannes A. Romijn, Ferdinand Roelfsema, Diane M. Sprij-Mooij, Maarten O. van Aken, Aart-Jan van der Lelij, Wouter W. de Herder, Steven W. J. Lamberts, Leo J. Hofland, Coexpression of dopamine and somatostatin receptor subtypes in corticotroph adenomas. The Journal of Clinical Endocrinology and Metabolism. ,vol. 94, pp. 1118- 1124 ,(2009) , 10.1210/JC.2008-2101