Actively maintained lipid nanodomains in biomembranes.

作者: Jordi Gómez , Francesc Sagués , Ramon Reigada

DOI: 10.1103/PHYSREVE.77.021907

关键词: MembraneBiophysicsLiquid ordered phaseMembrane fluidityMembrane biophysicsRaftNanotechnologyBiological membraneChemistrySphingolipidLipid raft

摘要: Lipid rafts, defined as domains rich in cholesterol and sphingolipids, are involved many important plasma membrane functions. Recent studies suggest that the way cells handle is fundamental formation of such lateral heterogeneities. We propose to model a nonequilibrium phase-separating system where dynamically incorporated released. The shows how cellular regulation may determine nanoscale lipid organization when mixture close phase separation boundary, providing plausible mechanism for raft vivo.

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