Photothermally triggered disassembly of a visible dual fluorescent poly(ethylene glycol)/α-cyclodextrin hydrogel
作者： Afeng Yang , Xia Dong , Jie Liang , Yan Zhang , Wenzhi Yang
DOI: 10.1039/C8SM00626A
关键词: Fluorescence-lifetime imaging microscopy 、 Ethylene glycol 、 Photothermal effect 、 Fluorescence 、 Materials science 、 Conjugated system 、 Photothermal therapy 、 Biophysics 、 Porphyrin 、 Self-healing hydrogels
摘要: The real-time tracking and adjustment of the disassembly status hydrogels in vivo are important challenges to accurate precise assessment. In this article, a photothermally controllable, visible, dual fluorescent thermosensitive hydrogel was designed developed based on porphyrin-poly(ethylene glycol)/IR-820-α-cyclodextrin hydrogel. Due photothermal effect fluorescence emission IR-820, it can exert functions control imaging tracking. IR-820 conjugated regulate by IR-820. Furthermore, each component be tracked porphyrin. Fluorescence remote were merged into visible controlled after subcutaneous injection using mice as models. visualization cyclodextrin/poly(ethylene glycol) revealed process component, efficiently accelerated under laser irradiation with This affords an basis for understanding poly(ethylene glycol)/α-cyclodextrin
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sci-hub.se 参考文章(46)
Jianqing Hu, Jinshan Guo, Zhiwei Xie, Dingying Shan, Ethan Gerhard, Guoying Qian, Jian Yang, Fluorescence imaging enabled poly(lactide-co-glycolide). Acta Biomaterialia. ,vol. 29, pp. 307- 319 ,(2016) , 10.1016/J.ACTBIO.2015.10.010
Joshua E. Mealy, Christopher B. Rodell, Jason A. Burdick, Sustained small molecule delivery from injectable hyaluronic acid hydrogels through host–guest mediated retention Journal of Materials Chemistry B. ,vol. 3, pp. 8010- 8019 ,(2015) , 10.1039/C5TB00981B
Ghulam Jalani, Rafik Naccache, Derek H. Rosenzweig, Sophie Lerouge, Lisbet Haglund, Fiorenzo Vetrone, Marta Cerruti, Real-time, non-invasive monitoring of hydrogel degradation using LiYF4:Yb3+/Tm3+ NIR-to-NIR upconverting nanoparticles Nanoscale. ,vol. 7, pp. 11255- 11262 ,(2015) , 10.1039/C5NR02482J
Jimei Zhang, Chan Li, Xu Zhang, Shuaidong Huo, Shubin Jin, Fei-Fei An, Xiaodan Wang, Xiangdong Xue, C.I. Okeke, Guiyun Duan, Fengguang Guo, Xiaohong Zhang, Jifu Hao, Paul C. Wang, Jinchao Zhang, Xing-Jie Liang, In vivo tumor-targeted dual-modal fluorescence/CT imaging using a nanoprobe co-loaded with an aggregation-induced emission dye and gold nanoparticles. Biomaterials. ,vol. 42, pp. 103- 111 ,(2015) , 10.1016/J.BIOMATERIALS.2014.11.053
Alicia Fernandez-Fernandez, Romila Manchanda, Denny Carvajal, Tingjun Lei, Supriya Srinivasan, Anthony McGoron, Covalent IR820-PEG-diamine nanoconjugates for theranostic applications in cancer. International Journal of Nanomedicine. ,vol. 9, pp. 4631- 4648 ,(2014) , 10.2147/IJN.S69550
Kathleen E. McGrath, Timothy P. Bushnell, James Palis, Multispectral imaging of hematopoietic cells: where flow meets morphology. Journal of Immunological Methods. ,vol. 336, pp. 91- 97 ,(2008) , 10.1016/J.JIM.2008.04.012
Elham Khodaverdi, Zinat Heidari, Sayyed A. Sajadi Tabassi, Mohsen Tafaghodi, Mona Alibolandi, Farnaz Sadat Mirzazadeh Tekie, Bahman Khameneh, Farzin Hadizadeh, Injectable supramolecular hydrogel from insulin-loaded triblock PCL-PEG-PCL copolymer and γ-cyclodextrin with sustained-release property. Aaps Pharmscitech. ,vol. 16, pp. 140- 149 ,(2015) , 10.1208/S12249-014-0198-4
Supriya Srinivasan, Romila Manchanda, Alicia Fernandez-Fernandez, Tingjun Lei, Anthony J. McGoron, Near-infrared fluorescing IR820-chitosan conjugate for multifunctional cancer theranostic applications. Journal of Photochemistry and Photobiology B-biology. ,vol. 119, pp. 52- 59 ,(2013) , 10.1016/J.JPHOTOBIOL.2012.12.008
Qingwei Zhang, Vadym N. Mochalin, Ioannis Neitzel, Isabel Y. Knoke, Jingjia Han, Christopher A. Klug, Jack G. Zhou, Peter I. Lelkes, Yury Gogotsi, Fluorescent PLLA-nanodiamond composites for bone tissue engineering. Biomaterials. ,vol. 32, pp. 87- 94 ,(2011) , 10.1016/J.BIOMATERIALS.2010.08.090
JinFeng Liao, WenTing Li, JinRong Peng, Qian Yang, He Li, YuQuan Wei, XiaoNing Zhang, ZhiYong Qian, Combined cancer photothermal-chemotherapy based on doxorubicin/gold nanorod-loaded polymersomes Theranostics. ,vol. 5, pp. 345- 356 ,(2015) , 10.7150/THNO.10731