Efficacy of Intermittent Colchicine Therapy in Familial Mediterranean Fever

作者: DANIEL G WRIGHT , SHELDON M WOLFF , ANTHONY S FAUCI , DAVID W ALLING

DOI: 10.7326/0003-4819-86-2-162

关键词: Internal medicineColchicineFamilial Mediterranean feverDiseaseProdromeMedicinePlaceboGeneral Medicine

摘要: Nine patients with familial Mediterranean fever (FMF) were admitted to a controlled, double-blind trial determine if there are this disease who able abort their acute episodes of pain and short courses colchicine taken at the onset attacks. Five completed treatment assignments, was significantly effective in aborting attacks three but ineffective two. The remaining four could not be assessed because insufficient numbers courses. During 10 months trial, 28 31 placebo during early stages FMF Twenty-one (75%) followed by considered have been aborted, compared only (10%) This shows that can recognize prodrome some consistently very symptoms.

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