作者: Yih-Choung Yu
DOI: 10.1002/0471732877.EMD039
关键词: Intensive care medicine 、 Cardiac surgery 、 Clinical tests 、 Surgery 、 Control theory 、 Mean arterial pressure 、 Intensive care unit 、 Medicine 、 Blood pressure 、 Automatic control 、 Control system
摘要: Automatic blood pressure control is a technique that regulates the infusion rates of pharmacological agents automatically to maintain patient’s mean arterial within desired level. Patients under regulation treatment are usually in cardiac surgery or suffering from postsurgical hypertension other diseases with abnormal pressure. This performed by experienced personnel operation room intensive care unit, which very difficult and time consuming. An automatic controller could deliver drugs based on physiologic conditions safely effectively without human intervention would be beneficial both patients medical personnel. This article reviews various schemes have been developed regulate for using sodium nitroprusside proportional-derivative-integral controllers, adaptive rule-based neural-network controllers common strategies described literature. A brief description each scheme provided, followed examples designs Evaluations performance computer simulation, animal studies, clinical tests subjects discussed. Keywords: blood regulation; biomedical systems; mathematical modeling; parameter estimation; drug delivery system