Effects of Morphine Opiates on Immune Function

作者: Hikmet Koyuncuoğlu , Mehmet Güngör

DOI: 10.1007/978-1-4899-0557-4_26

关键词: ThrombophlebitisAnesthesiaMedicineYoung adultCellulitisEndocarditisPneumoniaOpiateMortality rateHepatitis

摘要: The general anesthesia and surgery on the morphine opiate addicts,in which total blood volume cell mass had been found to be less than normal, were more problematic complicated patients prisoners in similar health conditions (Williams Oberst, 1946; Isbell, 1947; Eiseman et al., 1964). There is substantial evidence that addicts suffer from a mortality rate considerably higher what would expected relation their age. follow-up studies of addicted persons discharged treatment institutions reveal marked proportion died shortly after discharge although they mostly young adults. Among causes death postmortem examinations major medical complications addiction related use administration routes such as abscesses, cellulitis, endocarditis, hepatitis, pneumonia, septic pulmonary embolism, tetanus, thrombophlebitis etc. called up (Tolentino 1961; Cherubin, 1967; Louria Cherubin 1968; Espiritu Medina, 1980; Tarr, Sequeira 1982) ignoring fact are highly prone infectious diseases (Cherubin, 1967).

参考文章(172)
O. F. Eremina, L. V. Devoino, Production of humoral antibodies in rabbits after destruction of the nucleus of the midbrain raphe Bulletin of Experimental Biology and Medicine. ,vol. 74, pp. 58- 60 ,(1973) , 10.1007/BF00805388
N. D. Goldberg, M. K. Haddox, R. Estensen, J. G. White, C. Lopez, J. W. Hadden, Evidence of a Dualism between Cyclic GMP and Cyclic AMP in the Regulation of Cell Proliferation and Other Cellular Processes Cyclic AMP, Cell Growth, and the Immune Response. pp. 247- 262 ,(1974) , 10.1007/978-3-642-86026-3_20
Theodore J. Cicero, Thomas M. Badger, A Comparative Analysis of the Effects of Narcotics, Alcohol and the Barbiturates on the Hypothalamic-Pituitary-Gonadal Axis Alcohol Intoxication and Withdrawal—IIIb. pp. 95- 115 ,(1977) , 10.1007/978-1-4615-9038-5_8
M. Güngör, H. Sagduyu, H. Koyuncuoglu, Ö. Ang, V. Uysal, D. Inanç, M. Ang, Comparison of the development of experimental pyelonephritis in homozygous brattleboro diabetes insipidus rats, heterozygous control rats and normal wistar rats Infection. ,vol. 13, pp. 82- 84 ,(1985) , 10.1007/BF01660420
Robert George, Hypothalamus: Anterior Pituitary Gland Narcotic Drugs. pp. 283- 299 ,(1971) , 10.1007/978-1-4684-1869-9_13
Robert George, Emery Zimmermann, Narcotics and the hypothalamus Raven Press. ,(1974)
Robert M. Suskind, Malnutrition and the immune response. Infusionstherapie und klinische Ernährung. ,vol. 13, pp. 148- 171 ,(1986) , 10.1159/000412962
A.E. Axelrod, Anthony C. Trakatellis, RELATIONSHIP OF PYRIDOXINE TO IMMUNOLOGICAL PHENOMENA. Vitamins and Hormones Series. ,vol. 22, pp. 591- 607 ,(1964) , 10.1016/S0083-6729(08)60354-4
Singh U, Effect of catecholamines on lymphopoiesis in fetal mouse thymic explants. Journal of Anatomy. ,vol. 129, pp. 279- 292 ,(1979)