作者: Xiaohui Mei , Shirlynn Chen
DOI:
关键词: Protease 、 Bioavailability 、 Hepatitis c viral 、 Hepatitis C virus 、 Protease inhibitor (pharmacology) 、 Virology 、 Biology
摘要: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors having improved bioavailability, and methods using these for inhibiting the replication virus (HCV) treatment an HCV infection. These include co-solvent systems, lipid based solid dispersions granulations, all comprise inhibitor, at least one pharmaceutically acceptable amine optionally or more additional ingredients.