Pd-1 antibody

作者: Kerry Louise Tyson

DOI:

关键词: Computational biologyHeavy chainVariable domainMolecular biologySequence (medicine)Framework regionBiologyAntibody

摘要: A humanized agonistic antibody which binds human PD-1 comprising a heavy chain wherein the variable domain of comprises sequence given in SEQ ID NO:1 for CDR-H1, NO: 2 CDR-H2 and 3 CDR-H3 framework region is derived from sub-group VH4 3-1 4-30.4+JH4 (SEQ 33). The disclosure also extends to therapeutic uses molecules, compositions methods producing said molecules.

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