Method for the stimulation of T cells having a desired antigen specificity

摘要: T cells having a desired antigen specificity are stimulated by (a) introducing immortalizing genes into antigen-presenting in manner permitting regulation of the expression and/or function at least one these to achieve conditionally immortalized cells; (b) gene encoding be expressed after abolishment stops; (c) expanding functional activation genes; (d) completing proliferation stopping abolishing controllable (e) continuing antigen; (f) adding leucocytic including and cultivating cell mixture stimulate directed against (g) optionally purifying isolating cells.