作者: Robert M. Kacmarek
DOI: 10.1097/00004311-199903730-00007
关键词: Animal species 、 High peak 、 Pulmonary gas pressures 、 ARDS 、 Airway 、 Ventilator-associated lung injury 、 Medicine 、 Beneficial effects 、 Randomized controlled trial 、 Intensive care medicine 、 Anesthesiology and Pain Medicine
摘要: There is injury caused in numerous animal species when overdistending airway pressure and volume are delivered. The extent of this attenuated by the application PEEP. Patient case series point to benefit LPVS. In randomized controlled trials, data may appear confusing. However, based on from Amato colleagues' trial, it seems prudent employ an LPVS individual patient's lung mechanics. Based trials discussed appears that many have been convinced detrimental effects high peak alveolar pressure. It remains convince clinicians beneficial use higher PEEP early ARDS respiratory system mechanics patient recruitment maneuvers. conclusion, I concur with Dreyfuss Saumon Slutsky Tremblay not only attenuate severity preventing VALI, but also prevent MODS or its severity.