Bone tissue response to plasma-nitrided titanium implant surfaces

摘要: A current goal of dental implant research is the development titanium (Ti) surfaces to improve osseointegration. Plasma nitriding treatments generate that favor osteoblast differentiation, a key event process osteogenesis. Based on this, it possible hypothesize plasma-nitrided Ti implants may positively impact Objective The aim this study was evaluate in vivo bone response modified by plasma-nitriding treatments. Material and Methods Surface consisted 20% N2 80% H2, 450°C 1.5 mbar during 1 h for planar 3 hollow cathode. Untreated surface used as control. Ten each were placed into rabbit tibiae 6 weeks post-implantation they harvested histological histomorphometric analyses. Results Bone formation observed contact with all without statistically significant differences among evaluated terms bone-to-implant contact, area between threads, within mirror area. Conclusion Our results indicate plasma induce similar untreated ones. Thus, these physico-chemical properties affecting its biocompatibility, could be combined modifications order develop new surfaces.