Does G6PD deficiency protect against cancer? A critical review.

作者: P Cocco

DOI: 10.1136/JECH.41.2.89

关键词: Internal medicineGlucosephosphate Dehydrogenase DeficiencyOncologyMedicineEpidemiologyCancerLower mortalityImmunology

摘要: Previous observations on the lower mortality for cancer experienced in populations with a higher frequency of G6PD deficiency support biochemical studies role during cell proliferation. The general agreement among experimental prevented deeper analysis sources what has been called "epidemiological evidence protective against cancer". This review analyses methods and findings those papers, stressing their limitations emphasising that no final conclusions can be drawn from them. Preliminary results ongoing epidemiological are presented, although they do not prove or disprove hypothesis protects cancer.

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