11METHYLL33ISOPROPYLLCYCLOPENTANEE1* 22DICARBOXYLIC ACID AND ITS LOWER ALKYL ESTER AND TASTE MODIFIER FOR TOBACCO THEREFROM

摘要: NEW MATERIAL:Titled compound of the formula (R is H, methyl, ethyl or propyl). USE:Taste modifier for tobacco. PREPARATION: Leaves Turkish tobacco are extracted with isoprpyl ether and extract concentrated under reduced pressure. Then concentrate subjected to liquid-liquid extraction a sodution solium bicarbonate collect acid portion. The fraction chromatographed using column packed silicic in an amount 20-30 times weight solvent mix consisting 98 benzene 2 methanol. elucidate collected esterified diazomethane. methyl ester fractionated by gas chromatography isolate pure 1-methyl-3-isopropyl-cylcopetane-1,2-dicarboxylic dimethyl ester, from which other compounds derived.