Intradermal and serological tests with Dirofilaria immitis antigen in cases of human filariasis.

作者: John Bozicevich , A. M. Hutter

DOI: 10.4269/AJTMH.1944.S1-24.203

关键词: LymphangitisAntigenBiologyWuchereria bancroftiDirofilaria immitisSerial dilutionComplement fixation testFilariasisImmunologySerologyVirology

摘要: Summary All of 25 individuals suspected having Wuchereria bancrofti infections gave positive intradermal reactions with a 1:8,000 dilution an antigen prepared from Dirofilaria immitis while false in non-infected and allergic persons were screened out by the use this dilution. Only 4 had harbored helminth parasites other than W. sufficient evidence is therefore not available our tests to indicate whether abovementioned would satisfactorily screen which might be due these parasites. In some cases injection was followed exacerbations symptoms lymphangitis together pain scrotum inguinal glands. Negative complement fixation obtained above-mentioned saline ranging dilutions 1:100 1:1,600, although results rabbits immunized residue preparation. The alcoholic appeared inferior material. By testing 24 hours later D. material, local passive hypersensitivity elicited 6 recipients injected bood serum filariasis patients. Seven 12 died being preparation, fact seem that adult worms contain toxic substance.

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