Sarcomas of Bone

摘要: Sarcomas of bone have a number distinguishing features that set them apart from primary cancers many other organ systems. First, they are extremely rare in comparison with types cancer, fact has impeded the ability treatment this field to evolve rapidly an evidence-based manner because small numbers patients available for studies. Progress been possible only multicenter and oncology group trials can provide sufficient study. Even so, clinical generally limited prospective case series at best, much literature is based on retrospective series. True controlled randomized rare. Nevertheless, clinically useful observations defining behavior these tumors their responses treatments derived analyses numerous published, results associated levels evidence reviewed here.