Vitamins and Type 2 Diabetes Mellitus

摘要: The present review evaluates the relationship between type 2 diabetes mellitus and individual or combined vitamins. Antioxidant vitamins A, C E are found decreased in diabetic subjects, possibly due to an increased need control excessive oxidative stress produced by abnormalities glucose metabolism. On other hand, retinol binding protein exerts a modulating effect, as it has adipokine functions. With respect B group vitamins, thiamin, pyridoxine biotin have been but mechanisms not clear, however supplementation shown some improvement of metabolic patients. absorption folic acid vitamin B12 is importantly prolongued use metformin, which first choice drug uncomplicated diabetes, thus these two nutrients deficient disease most probably be supplemented regularly. D considered risk factor for development well its complications, particularly cardiovascular ones. Although studies association K intake with metabolism further research needed. Studies on multivitamin supplements unconclusive results. After reviewing evidence, no real recommendation can issued, patients using metformin during periods may B12.