Succinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and Epigenetics

作者: Yeng F. Her , L. James Maher

DOI: 10.1155/2015/296167

关键词: Succinate dehydrogenaseAtp productionMalignancyFamilial ParagangliomaEpigeneticsGeneticsBiologyCitric acid cycleCancerBiochemistry

摘要: … This review focuses on the effects of loss of succinate dehydrogenase (SDH). SDH is part of both the TCA cycle and the ETC. In the TCA cycle, SDH catalyzes the oxidation of …

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