The menstrual cycle and the skin

摘要: Perimenstrual exacerbations of dermatoses are commonly recognized, yet our knowledge the underlying pathophysiological mechanisms remains imperfect. Research into effects oestrogen on skin has provided evidence to suggest that is associated with increases in thickness and dermal water content, improved barrier function, enhanced wound healing. progesterone suggests presence various correlates peak levels progesterone. Dermatoses exacerbated perimenstrually include acne, psoriasis, atopic eczema irritant dermatitis, possibly also erythema multiforme. Exacerbations occur at menstrual cycle. Underlying reduced immune functions as a result cyclical fluctuations and/or Autoimmune dermatitis best-characterized examples perimenstrual cutaneous reactions hormones produced during In this review, we describe current understanding cycle, its effect disorders.