Pulmonary tuberculosis in BALB/c mice with non‐functional IL‐4 genes: changes in the inflammatory effects of TNF‐α and in the regulation of fibrosis

作者: Rogelio Hernandez-Pando , Diana Aguilar , Maria Luz Garcia Hernandez , Hector Orozco , Graham Rook

DOI: 10.1002/EJI.200324253

关键词: Interferon gammaFibrosisMycobacterium tuberculosisBALB/cBiologyEndocrinologyInternal medicineHydroxyprolineInterleukin 4ImmunologyToxicityTumor necrosis factor alpha

摘要: … tuberculosis. Delayed-type hypersensitivity (DTH) sites in IL-4 +/+ mice were sensitive to the toxicity of locally injected TNF-… There are mouse models of TB in which IL-4 does not play an …

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