Functional connectivity between memory and reward centers across task and rest track memory sensitivity to reward.

摘要: External motivation, such as a promise of future monetary reward for remembering an event, can affect which events are remembered. Reward-based memory modulation is thought to result from encoding and post-encoding interactions between dopaminergic midbrain, signaling reward, hippocampus parahippocampal cortex, supporting episodic memory. We asked whether hippocampal with other reward-related regions related relationships stable over time. Individuals’ sensitivity was measured using incentive task in cue indicated potential (penny, dime, or dollar) upcoming object pair. Functional connectivity before, during, following the task. Reward-related interest were generated meta-analysis existing studies on included ventral striatum, medial orbital prefrontal cortices anterior cingulate addition midbrain. The results showed that tracked individual differences memory, irrespective when measured. Connectivity patterns cingulate, orbitofrontal striatum covaried together behavior most strongly. These findings implicate broader set than considered previously provide new evidence centers relate how impacts