A non-invasive, bioimpedance-based 2-dimensional imaging system for detection and localization of pathological epithelial tissues

作者: Congo Tak-Shing Ching , Jhih-Hao Chen

DOI: 10.1016/J.SNB.2014.09.072

关键词: Pressure soresNon invasiveTongue CancersBiomedical engineeringPathologicalStatistical differenceAnalyserAnalytical chemistryStandard deviationComputer science

摘要: Abstract The aim of this study is to design, construct and evaluate a 2-dimensional (2D) imaging system based on measurements bioimpedance, for non-invasive detection localization pathological epithelial tissues. Results show that the designed equally accurate in measuring bioimpedance over range frequencies (10 Hz 50 kHz), when compared with precision impedance analyser (WK6420C), no significant statistical difference ( P  > 0.05) found error below 0.5%. Moreover, made by WK6420C were comparable reproducible each other, as confirmed Bland–Altman plots showing all points (i.e. differences between pair from WK6420C) located within ±2 standard deviation lines. Additionally, vitro situ studies showed capable identifying tissues generated 2D image our software can visually provide direct information screening diagnosis. Finally, theoretically be used screenings variety illnesses, such tongue cancers pressure sores. provides additional tool tele-diagnosis/screening rural area.

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