Health-related quality of life after surgery for advanced and recurrent rectal cancer: a nationwide prospective study.
作者： H. V. Thaysen , P. Jess , P. C. Rasmussen , M. B. Nielsen , S. Laurberg
DOI: 10.1111/CODI.12551
关键词: Level of functioning 、 Prospective cohort study 、 Surgery 、 Colorectal cancer 、 Medicine 、 Total mesorectal excision 、 Health related quality of life 、 Recurrent Rectal Cancer 、 University hospital 、 Quality of life
摘要: Aim Advances in the treatment of rectal cancer have made it possible to perform complex surgery (COMP-RCS) patients with primary advanced penetrating beyond total mesorectal excision planes and locally recurrent cancer. The aim this study was examine health-related quality life (HRQoL) before during first 2 years after COMP-RCS. Method Between 2001 2008, 180 were treated COMP-RCS at Aarhus University Hospital. HRQoL assessed preoperatively 3, 6, 12, 18 24 months using three questionnaires. results compared those for standard (STAN-RCS) data from general Danish population (NORM-data). Results One hundred twenty-two (68%) responded Of these 80 (66%) disease-free survival included main analysis. lowest level functioning highest degree symptoms reported preoperatively. majority scales improved or remained stable postoperative year; a decrease observed body image only. One year surgery, COMP-RSC comparable that STAN-RCS. Lower levels found physical emotional role functioning, NORM-data. Conclusion Patients experienced improvement surgery. similar Compared NORM-data, lower functioning.
sci-hub.se 参考文章(34)
Jakob B. Bjorner, Kate Thunedborg, Tage S. Kristensen, Jens Modvig, Per Bech, The Danish SF-36 Health Survey: Translation and Preliminary Validity Studies Journal of Clinical Epidemiology. ,vol. 51, pp. 991- 999 ,(1998) , 10.1016/S0895-4356(98)00091-2
, Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes. British Journal of Surgery. ,vol. 100, pp. 1009- 1014 ,(2013) , 10.1002/BJS.9192_1
M. B. Nielsen, S. Laurberg, T. Holm, Current management of locally recurrent rectal cancer. Colorectal Disease. ,vol. 13, pp. 732- 742 ,(2011) , 10.1111/J.1463-1318.2009.02167.X
D Osoba, G Rodrigues, J Myles, B Zee, J Pater, Interpreting the significance of changes in health-related quality-of-life scores. Journal of Clinical Oncology. ,vol. 16, pp. 139- 144 ,(1998) , 10.1200/JCO.1998.16.1.139
F. T. J. Ferenschild, M. Vermaas, C. Verhoef, A. C. Ansink, W. J. Kirkels, A. M. M. Eggermont, J. H. W. de Wilt, Total pelvic exenteration for primary and recurrent malignancies. World Journal of Surgery. ,vol. 33, pp. 1502- 1508 ,(2009) , 10.1007/S00268-009-0066-7
Johan N Wiig, Jan P Poulsen, Stein Larsen, Morten Brændengen, Håkon Wæhre, Karl‐Erik Giercksky, None, Total pelvic exenteration with preoperative irradiation for advanced primary and recurrent rectal cancer. European Journal of Surgery. ,vol. 168, pp. 42- 48 ,(2002) , 10.1080/110241502317307562
J. D. Smith, G. M. Nash, M. R. Weiser, L. K. Temple, J. G. Guillem, P. B. Paty, Multivisceral resections for rectal cancer. British Journal of Surgery. ,vol. 99, pp. 1137- 1143 ,(2012) , 10.1002/BJS.8820
Uffe S Løve, Pia Sjøgren, Peter Rasmussen, Søren Laurberg, Henrik K Christensen, None, Sexual dysfunction after colpectomy and vaginal reconstruction with a vertical rectus abdominis myocutaneous flap. Diseases of The Colon & Rectum. ,vol. 56, pp. 186- 190 ,(2013) , 10.1097/DCR.0B013E31826E4BD5
Evita Zoucas, Sven Frederiksen, Marie-Louise Lydrup, Wiking Månsson, Pelle Gustafson, Per Alberius, Pelvic Exenteration for Advanced and Recurrent Malignancy World Journal of Surgery. ,vol. 34, pp. 2177- 2184 ,(2010) , 10.1007/S00268-010-0637-7
A. Bhangu, G. Brown, M. Akmal, P. Tekkis, Outcome of abdominosacral resection for locally advanced primary and recurrent rectal cancer British Journal of Surgery. ,vol. 99, pp. 1453- 1461 ,(2012) , 10.1002/BJS.8881