Pharmacology of heparin and warfarin

作者: Stanford Wessler , Sanford N. Gitel

DOI: 10.1016/S0735-1097(86)80003-1

关键词: WarfarinIntensive care medicineAnticoagulant prophylaxisMedicinePremature deathAnesthesiaRelative riskDrugHeparinVascular diseaseAntithrombotic

摘要: Thromboembolic obstruction to three major components of the circulation—arterial, venous and intravascular foreign surfaces—contributes premature death disability in Western society. In many, but not all, these conditions associated with thromboembolism, heparin warfarin are drugs choice. It is purpose this presentation provide some common ground area anticoagulant prophylaxis that will be intrinsic value for decision making cardiac, cerebral peripheral vascular disease. Only those aspects hemostatic mechanism most relevant antithrombotic action discussed. Assays both as well practical guidelines their use low, medium high dose regimens outlined. Techniques improving benefit/risk ratio each drug specifically detailed.

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