Levels of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in breast milk in Shanghai, China: A temporal upward trend

摘要: Abstract Human milk samples were collected from 150 mothers in 2011 and 2012 Shanghai, China analyzed for 17 polychlorinated dibenzo- p -dioxins/furans (PCDD/Fs) 12 dioxin-like biphenyls (DL-PCBs). The up-bound Toxic Equivalent Quantity (TEQ) ranged 0.27 to 16.8 pg TEQ/g lipid (mean 5.4 pg lipid) ∑PCDD/Fs 0.75 10.2 pg 2.9 pg ∑DL-PCBs. TEQs our study lower than those most countries worldwide, displayed a notable uptrend, contrast with China’s national survey 2007. mother milks urban areas higher rural areas, an orderly distribution was found four geographical regions: Eastern China > Central China ≈ Southwestern China > Northwestern China. Levels of analytes Shanghai native mothers’ ranked the first among all provinces cities investigated. Migrant other inland could potentially represent population exposure risk assessment their birth grown-up places. Both uptrend associated release these pollutants due rapid industrialization urbanization Fine correlations observed between age mothers, weak consumption meat & products. Participants, who preferred both fresh water marine fish freshwater only, prone be exposed level PCBs. estimated daily intake (EDI) doses breastfed neonates entirely exceeded tolerable dose by WHO.