Brain mechanisms of taste aversion learning in the rat.

作者: Takashi Yamamoto , Yoshiyuki Fujimoto

DOI: 10.1016/0361-9230(91)90133-5

关键词: AmygdalaIbotenic acidSubstantia innominataHippocampusNeuroscienceTaste aversionStria terminalisClassical conditioningPsychologyEntorhinal cortex

摘要: This study aims to reveal brain mechanisms underlying the conditioned taste aversion (CTA) learning. To establish CTA in Wistar male adult rats, 0.01 M Na-saccharin and IP injection of 0.15 LiCl were used for stimulus unconditioned stimulus, respectively. Rats with ibotenic acid lesions pontine area, thalamic or basolateral nucleus amygdala, failed learning, but amygdaloid nuclei other than nucleus, cortical gustatory hippocampus, entorhinal cortex, bed stria terminalis, substantia innominata, showed slight little effects. that received amino-phosphovaleric chronically amygdala CTA. These results, together our preliminary suggest long-term potentiation responses involving N-methyl-D-aspartate receptors is a basic mechanism

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