Secondary Metabolites and PI3K Inhibitory Activity of Colletotrichum gloeosporioides , a Fungal Endophyte of Uncaria rhynchophylla
作者： Zhong-Duo Yang , Zhi-Jie Li , Jun-Wen Zhao , Jian-Hui Sun , Li-Jun Yang
DOI: 10.1007/S00284-019-01707-7
关键词: Colletotrichum 、 Brevianamide F 、 Biochemistry 、 Mellein 、 Biology 、 Ergosterol peroxide 、 Inhibitory postsynaptic potential 、 Ergosterol 、 Uncaria rhynchophylla 、 Bran
摘要: In the present study, nine compounds (1–9) were isolated from Colletotrichum gloeosporioides (an endophytic fungus from Uncaria rhynchophylla) which was cultured in wheat bran medium. Their structures were elucidated as 4-Epi-14-hydroxy-10, 23-dihydro-24, 25-dehydroaflavinine (1), 10, 23-Dihydro-24, 25-dehydro-21–oxoaflavinine (2), Ergosterol (3), Ergosterol peroxide (4), Mellein (5), 4, 5-dihydroblumenol A (6), Colletotrichine A (7), Cyclo (L-leucyl-L-leucyl)(8), and Brevianamide F (9) based on NMR …
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