Charming neighborhoods on the cell surface: plasma membrane microdomains regulate receptor tyrosine kinase signaling.

作者: Ralph Christian Delos Santos , Camilo Garay , Costin N. Antonescu

DOI: 10.1016/J.CELLSIG.2015.07.004

关键词: Cell biologyReceptor tyrosine kinaseTransport proteinBiologySignal transductionCaveolaeClathrinTetraspaninReceptor Protein-Tyrosine KinasesLipid raft

摘要: … Peptides corresponding to caveolin's CSD rescued IR expression levels in Cav-1 deficient MEFs and directly stimulated IR kinase activity in HEK-293T cells [72], [73], [75], [77]. …

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