The relationship between nonsteroidal anti-inflammatory drug use and peptic ulcer disease.

作者: David Y. Graham

DOI: 10.1016/S0889-8553(21)00463-5

关键词: Perforation (oil well)Peptic Ulcer PerforationMedicineInternal medicineUpper gastrointestinal bleedingDrugAnti-inflammatoryArthritisGastroenterologyComplicationDisease

摘要: It has become increasingly recognized that nonsteroidal anti-inflammatory drug (NSAID) use is associated with serious gastroduodenal mucosal injury can eventuate in upper gastrointestinal bleeding or perforation. This article discusses the lack of predictive value studies administering NSAIDs to normal volunteers. The new data concerning prevention and treatment chronic NSAID ulcers also discussed.

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