Prevalence and Health Outcomes of Functional Gastrointestinal Symptoms in Infants From Birth to 12 Months of Age

摘要: Objectives: The aim of the study was to review published evidence and opinion practising clinicians on prevalence long-term health consequences functional gastrointestinal symptoms in infants younger than 12 months. Methods: PubMed searched from inception November 2014 find articles reporting outcomes infantile colic, regurgitation, constipation, diarrhoea, dyschezia <12 A questionnaire sent worldwide, a group 15 international experts met discuss likely frequency longer-term these symptoms. Results: literature search identified 30 studies colic (2%-73%), 13 that regurgitation (3%-87%), 8 constipation (0.05%-39.3%), 2 diarrhoea (2%-4.1%), 3 (0.9%-5.6%). varied design, populations investigated, definition Questionnaires were received 369 respondents. agreed prevalences for 20%, 30%, 15%, respectively. limited data suggest <10%. Infantile may be associated with future problems subset infants. Conclusions: Functional appear occur significant proportion months have an impact outcomes. Prospective collection according criteria is needed obtain more accurate estimates