Transport of radioactivity from eye to visual cortex in the mouse.

摘要: Abstract After injection of tritiated proline into the mouse eye, radioactive protein was axonally transported in optic nerve to lateral geniculate body. Five hours after its initial appearance geniculate, labeled also began appear visual cortex. Thereafter, amount cortex closely related during arrival both fast and slow components axonal transport (and possibly an intermediate component as well). The proportion accumulating relative that steadily increased with time. rate increase identical normal mice mutant which electrical activity probably reduced because absence receptors. It appeared likely, therefore, accumulation unrelated activity. Leucine glucosamine were less satisfactory than for demonstrating cortical accumulation, fucose better proline. tentative picture emerging from these experiments is there a constant transfer axons neuronal elements their vicinity. This not process synaptic transmission.