Molecular breast imaging with directly opposing compact gamma cameras

摘要: The goal of this study was to evaluate the efficacy operating a two-head gamma camera system in configuration which two cameras are positioned on opposite sides compressed breast, aligned precisely with each other and anti-parallel viewing directions. main objective present determine if combination resulting images might allow for better sensitivity small lesions all regions breast. Two pairs were evaluated; one composed commercially available research-based cameras. For pair, an acrylic box phantom, spherical suspended inside, used contrast SNR as function lesion position, first from separately then obtained pixel- by-pixel multiplication or summation individual images. A capillary phantom quantify spatial resolution depth individually well multiplied Lastly, gelatin phantoms imaged, containing single cube-shaped ~8 mm side length at varying depths within phantom. Relative summed images, image superior, irrespective depth, much more constant changing depth. Except when less than centimeter cameras, exceeded that using twice acquisition time. These findings suggest improved detectability is possible by imaging simultaneously both especially location breast not known priori.