Clinical and neurocognitive features of the post Lyme syndrome

摘要: Objective. To evaluate neurocognitive impairment in patients with persistent arthralgia, fatigue, and subjective memory loss after Lyme disease (post-Lyme syndrome, PLS). Methods. We compared the clinical, neurocognitive, psychological features of 23 PLS to age, sex, education matched recovered (REC). All met Centers for Disease Control criteria disease, were ELISA positive at onset previously treated standard antibiotic regimens. Results. Of PLS, 7 (30%) had fibromyalgia (FM), 3 (13%) chronic fatigue 10 (43%) similar but milder symptoms did not meet either. 22 complained decreased or concentration problems. Patients significantly lower scores on attention/concentration scale (p = 0.012) Wechsler Memory Scale-Revised (WMS-R), indicating lowered attention/concentration. 52% 35% REC group < 0.05) WMS-R verbal than visual scores. The subjectively more problems sleep mood changes higher several scales Symptom Check List 90-R 0.01), greater physical distress. Beck Depression Inventory also 0.005), within normal range. Conclusion. Despite treatment, a sequelae may be characterized by that is probably induced disease.