Blood levels of organochlorine pesticides in Argentina: Occupationally and nonoccupationally exposed adults, children and newborn infants☆

作者: J RADOMSKI

DOI: 10.1016/0041-008X(71)90044-5

关键词: Placental barrierToxicologyOrganochlorine pesticidePesticideChemistryDieldrinPhysiologyLindane

摘要: Abstract Determination of the concentration organochlorine pesticides has been made in adults, children, newborn infants, and various groups occupationally exposed individuals Argentina. β-HCH levels adults Argentina are approximately 16 times higher, on average, than found U.S. In contrast, concentrations p,p′ -DDE, dieldrin, -DDT closely similar to those Concentrations children lower, but still higher U.S., much children. Pesticide workers handling HCH were extremely high, as DDT isomers this pesticide. No dieldrin was detected these workers—a possible indication that microsomal stimulation by may have responsible for clearing tissues. The DDE:DDT ratio appeared be an accurate measurement a recent exposure DDT. Pesticides passed placental barrier, transmission apparently somewhat retarded. -DDT, 40% pesticide blood mother. This percentage α-HCH, lindane.

参考文章(6)
A. A. Nelson, O. G. Fitzhugh, J. P. Frawley, The chronic toxicities of technical benzene hexachloride and its alpha, beta and gamma isomers. Journal of Pharmacology and Experimental Therapeutics. ,vol. 100, pp. 59- 66 ,(1950)
William E. Dale, August Curley, Cipriano Cueto, Hexane extractable chlorinated insecticides in human blood Life Sciences. ,vol. 5, pp. 47- 54 ,(1966) , 10.1016/0024-3205(66)90186-X
J RADOMSKI, Human pesticide blood levels as a measure of body burden and pesticide exposure. Toxicology and Applied Pharmacology. ,vol. 20, pp. 175- 185 ,(1971) , 10.1016/0041-008X(71)90043-3
B. Davidow, J. P. Frawley, Tissue distribution, accumulation and elimination of the isomers of benzene hexachloride. Experimental Biology and Medicine. ,vol. 76, pp. 780- 783 ,(1951) , 10.3181/00379727-76-18631