Low-dose, long-term, intermittent interferon-alpha-2b therapy after radical treatment by radiofrequency ablation delays clinical recurrence in patients with hepatitis C virus-related hepatocellular carcinoma.

作者: Yasuhiro Sakaguchi , Masatoshi Kudo , Toyokazu Fukunaga , Yasunori Minami , Hobyung Chung

DOI: 10.1159/000082097

关键词: Clinical recurrenceOncologyIn patientInternal medicineInterferonHepatocellular carcinomaAlpha interferonRadical treatmentHepatitis C virusRadiofrequency ablationMedicine

摘要: Objective: To assess whether or not interferon (IFN) therapy prevents recurrence, and eventually improves the prognosis of patients with hepatocellular carcinoma (HCC) after complet

参考文章(29)
Isaburo Fujimoto, Yoshinori Urano, Aya Hanai, Kunio Okuda, Changing incidence of hepatocellular carcinoma in Japan. Cancer Research. ,vol. 47, pp. 4967- 4972 ,(1987)
Daniela Santoli, Hilary Koprowski, Giorgio Trinchieri, Spontaneous Cell-Mediated Cytotoxicity in Humans: Role of Interferon and Immunoglobulins Journal of Immunology. ,vol. 120, pp. 1849- 1855 ,(1978)
Shoji Kubo, Shuhei Nishiguchi, Kazuhiro Hirohashi, Hiromu Tanaka, Tadashi Tsukamoto, Taichi Shuto, Shigekazu Takemura, Takatsugu Yamamoto, Takashi Ikebe, Kenichi Wakasa, Susumu Shiomi, Hiroaki Kinoshita, Influence of previous interferon therapy on recurrence after resection of hepatitis c virus-related hepatocellular carcinoma. Japanese Journal of Cancer Research. ,vol. 92, pp. 59- 66 ,(2001) , 10.1111/J.1349-7006.2001.TB01048.X
Hong Ding, Masatoshi Kudo, Hirokazu Onda, Yoichiro Suetomi, Yasunori Minami, Kiyoshi Maekawa, Contrast-Enhanced Subtraction Harmonic Sonography for Evaluating Treatment Response in Patients with Hepatocellular Carcinoma American Journal of Roentgenology. ,vol. 176, pp. 661- 666 ,(2001) , 10.2214/AJR.176.3.1760661
Hong Ding, Masatoshi Kudo, Hirokazu Onda, Yoichiro Suetomi, Yasunori Minami, Hobyung Chung, Toshihiko Kawasaki, Kiyoshi Maekawa, Evaluation of posttreatment response of hepatocellular carcinoma with contrast-enhanced coded phase-inversion harmonic US: comparison with dynamic CT. Radiology. ,vol. 221, pp. 721- 730 ,(2001) , 10.1148/RADIOL.2213010358