The Role of Oxidative Stress in the Pathological Sequelae of Alzheimer Disease

作者: Mark A. Smith , George Perry

DOI: 10.1007/978-1-4757-2907-8_19

关键词: PathologyDisease processNeurofibrillary tangleSenile plaquesAlzheimer's diseaseMedicineHeme oxygenasePathologicalOxidative stressDisease

摘要: Oxidative stress and damage are accepted features of degenerating at risk neuronal populations in Alzheimer disease (Smith et al., 1994a,b, 1995a, 1996a, 1997a,b; Sayre 1997a). Nonetheless, there is controversy concerning how oxidative meshes with currently hypotheses as well whether an initiator the or instead a result process (Figure 1).

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