Tumor Neovasculature-Targeted APRPG-PEG-PDLLA/MPEG-PDLLA Mixed Micelle Loading Combretastatin A-4 for Breast Cancer Therapy
作者： Ying Hao , Jinrong Peng , Yaguang Zhang , Lijuan Chen , Feng Luo
DOI: 10.1021/ACSBIOMATERIALS.7B00523
关键词: Drug 、 Materials science 、 PEG ratio 、 Zeta potential 、 Combretastatin 、 Drug carrier 、 Combretastatin A-4 、 Biomedical engineering 、 Cytotoxicity 、 Biophysics 、 Micelle
摘要: … In this study, combretastatin A-4 (CA-4) loaded 5-amino acid … CA-4 is an effective vascular disrupting agent. The APRPG-… of CA-4 from the mixed micelles while compared to free CA-4. …
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