RAPID REACTIVE OXYGEN SPECIES (ROS) GENERATION INDUCED BY CURCUMIN LEADS TO CASPASE-DEPENDENT AND -INDEPENDENT APOPTOSIS IN L929 CELLS
作者： Faisal Thayyullathil , Shahanas Chathoth , Abdulkader Hago , Mahendra Patel , Sehamuddin Galadari
DOI: 10.1016/J.FREERADBIOMED.2008.08.014
关键词: Caspase 3 、 Apoptosis-inducing factor 、 Caspase 、 Cytochrome c 、 Cell biology 、 Molecular biology 、 Apoptosis 、 Reactive oxygen species 、 Biology 、 Mitochondrion 、 Poly ADP ribose polymerase
摘要: … has been shown to induce apoptosis in different malignant cancer cell lines [10]. … Moreover, our study shows that antioxidants such as GSH and NAC inhibit curcumin-induced cell death, …
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