Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays

作者: Gunars Edwin Valkirs , Kenneth Francis Buechler

DOI:

关键词: StereochemistryAntibodyChemistryReceptorLigand binding assayLigandProtein ligandBiochemistry

摘要: Methods and test devices for detecting the presence or amount of target ligand in non-competitive sandwich ligand-receptor assay processes. Antibodies which bind to complex receptor but do not significantly with substantially less affinity than are taught their uses described. These assays can be used eliminate "hook" effect assays. Furthermore, antibodies selected methods described so that, as a result process, no detectable response is observed due binding antibody absence ligand.

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